Rethinking how membranes are made.

Bringing new products and processes to the industrial landscape.

Membrane proteins regulate transport of various ions and molecules across cell membranes through a selective transport mechanism. Aquaporin proteins, for example, selectively transport water – and nothing but water – across the cell membrane. We believe we can use natural and modified proteins to build industrial membranes that are only permeable to water molecules and other ions and molecules of interest. The production of proteins is a well-understood and comercialized process, as is the production of conventional membranes. The key to moving the technology forward is to embed the proteins into nanostructures which can be incorporated into an industrial membrane that can withstand the operating conditions of a processing facility while continuing to deliver the performance required.
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Our Challenge

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Conventional membrane technologies have enabled decades of progress in purification and recovery of water and other resources, but they remain constrained by fundamental material and manufacturing limitations. Their performance relies on fabrication processes that introduce structural variability, which often force trade-offs between permeability, rejection, and selectivity, making it difficult to achieve application specific performance without compromising efficiency. As water treatment challenges become increasingly demanding, the industry requires a new approach to membrane design that moves beyond the constraints of conventional materials and architecture.

Our Approach

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Our biomimetic membrane platform is designed to overcome the fabrication, structural, and performance limitations of conventional membrane technologies. At the core of our approach is a thin nanostructured layer densely integrated with membrane transport proteins. This functional layer can be combined with a wide range of porous support membranes, creating a versatile platform for application specific membrane design.

 

By decoupling membrane function from conventional fabrication constraints, we can achieve greater control over membrane uniformity, transport characteristics, and durability. The result is a new generation of separation products engineered to deliver the performance, robustness, and reliability required for industrial applications.

 

Our goal is simple: develop membranes that adapt to industry needs, rather than forcing industry to adapt to membrane limitations.

Our Adaptability

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We have all the building blocks for almost any separation challenge. We can choose a specific membrane protein that defines the selectivity for a given application. Likely, this protein can be found in nature. If not, we have the potential to design it. Once we have that, we then need to embed this protein into our nanostructures and cover it with a support membrane.

 

The ability to arrive at this highly “selective blanket” is due to the versatility of our technology, along with three important steps in the process: substrate production, nanoparticle production, and membrane coating.

THE PROCESS

The world’s most efficient purification mechanism has evolved over eons: the membrane transport protein.

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Nanoparticle Production

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Manufacturing proteins is a well understood process. It’s used in everything from brewing beer and wine-making to delivering high-quality nutrition and healthcare. We’ve developed the capacity to produce and purify proteins in large bioreactors with high yield. Our challenge lies in encapsulating the proteins in nanoparticles that can deliver a robust component which provides functionality when incorporated into an industrial product.

 

Membrane proteins perform wonderfully in their native environments, but industrial applications push them to their limits. They operate at high temperatures, pressures, and extreme pH conditions. We need to ensure the proteins can be used in a product that delivers a meaningful performance advantage over conventional technology and allows them to perform in industrial conditions.

 

Addressing this gap was one of the biggest challenges we faced. We’ve solved it through patent protected designs and processes for protein formulation.

Substrate Production

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Conventional polymeric membranes used as substrates for polyamide coating processes do not deliver the characteristics needed for coating with a protein layer. The substrate material needs to be compatible with the protein layer. The pore size needs to be of similar size as the protein nanostructure. Plus, the membrane thickness should be as thin as possible but as robust as needed for the application.

 

Critical to a successful end product is a high-performance substrate that is designed and manufactured to tolerances that are beyond conventional technology and can be delivered at a competitive cost. We have formulated membranes and developed manufacturing processes that provide a consistent membrane surface on which we can coat our protein nanostructures.

Membrane Coating

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Marrying the protein nanoparticles with the substrate provides our final coated membrane. Conventional coating processes and chemistries don’t permit proteins to perform optimally. We’re developing in-house coating processes to enable the protein channels to deliver the results they’re naturally capable of – high efficiency, high selectivity, and low energy transport of targeted molecules.

Contact us today to learn more about how we can help you achieve your sustainability goals.